The research, conducted by Marcus Shürks, a researcher at Brigham and Women's Hospital in Boston, looked at nine international trials involving more than 118,000 study participants.
A total of 59,357 participants took vitamin E supplements, while the rest received placebo.
Based on their results, the researchers estimated that there could be an additional hemorrhagic stroke for every 1,250 people who took vitamin E.
An ischemic stroke, on the other hand, could be prevented for every 476 people who took vitamin E.